When Mark Davis, a chemical engineer, found out that his wife, Mary, had cancer, helping her survive devastating chemotherapy treatments became his mission. Her treatments became so unbearable that she pleaded with her husband to find a better way. “You can fix this,” she challenged him, and so began a scientific odyssey that led Davis to create IT-101, a revolutionary cancer drug. In the following Q&A, Davis discusses the drug he created and the hope it has already brought.
Q. How and why has cancer been so difficult to treat after so many years?
DAVIS: Cancer is really not a single disease - it is really over a 100 different types of diseases. What I mean by this is that lung cancer is different from breast cancer that is different of other types of cancer. Additionally, cancer is your own cells “gone mad” so the recognition of them from yourself is very difficult. These and other issues make cancer a very difficult disease to treat. However, the molecular level understanding of cancer is progressing at a very fast pace now and I believe that we will see spectacular advances in the near future as we exploit this new understanding.
Q. Please provide a quick background on how you came to develop IT-101.
DAVIS: This is the Curious story. I am an engineer so my approach was to ask what are the essential features that would need to be done to create a new cancer therapeutic that could overcome some of the current limitations. While one can never completely answer the question, certain issues could be defined. I then began to think about how to design a material and system to address those issues. That approach has yielded IT-101 and other new therapeutics that are now coming along behind IT-101. The key was not to take known materials and try to “bandage them up” to make them work, but rather to start from the beginning and build a system that is designed to function appropriately for the specific job.
Q. How does IT-101 differ from traditional cancer treatments? How is it unique?
DAVIS: Again, this is the Curious story. The way I describe it - it is the first de novo designed cancer medicine to reach humans.
Q. Did you have any previous experience with medical or biological research prior to developing IT-101?
DAVIS: Yes. My undergraduate training was in chemical engineering and pre-med. One of my undergraduate research projects was on nerve function. However, as a faculty member, I did not work on this until after Mary contracted breast cancer.
Q. How is your wife doing now?
DAVIS: She is doing fine. At this point, it is the chemo damage that affects her life, e.g., loss of high frequency hearing.
Q. Can you briefly outline and explain the FDA’s clinical trial process and what the different stages are?
DAVIS: Phase I - is it safe and what dose can be given to patients in a safe manner? What are the side effects and are they acceptable? Phase II - first look at how effective it is in a patient population large enough to be able to generate responses that can have statistical significance. Phase III - pivotal studies with large patient populations to see if the proposed therapy (dose level, dose schedule) provides any advance over current therapies.
Q. Where does the IT-101 trial stand now?
DAVIS: It is finishing the Phase I trial and will be moving into several Phase II trials (Phase I can be for all types of cancer but Phase II has to be in specific cancer types).
Q. Were you surprised at the initial success of the trial?
DAVIS: Yes. Especially at the first dosing showing effects.
Q. Has your research been specific to the kind of cancer your first trial patient, Ray Natha, has?
DAVIS: Ray has metastatic pancreatic cancer. IT-101 is not specific to that cancer. Our research has emphasized the creation of new therapeutics that would be broadly applicable to many types of cancer.
Q. How have the trial results compared in people with other types of cancer? Have they been similar?
DAVIS: Other patients have other cancer types. We are seeing effects in other cancer types but I am not able to provide you specific details.
Q. How did your relationship with City of Hope get established?
DAVIS: It was through Mary being treated there.
Q. How is Ray Natha doing today?
DAVIS: Ray is still be treated on compassionate use. He remains stable!
Q. What happens to patients after a trial concludes? Do they still have access to the treatments?
DAVIS: Thus far, patients who have successfully concluded the six-month trial are placed on compassionate use.
Q. Where can people go for an opportunity to participate in trials of experimental drugs?
DAVIS: There is a Web site that lists all the clinical trials ongoing.
Q. What are your hopes for the future of cancer treatment? Might there one day be a prophylactic approach to treatment, whereby patients can take preventative or maintenance drugs?
DAVIS: As I say, this is my dream - prophylactic use. We are, in fact, working on the concept of maintenance therapy right now. It is the logical step toward ultimately getting to prophylatic use.
Q. If all goes well, when do you expect IT-101 to be approved by the FDA and on the market?
DAVIS: Three to seven years.
Q. Have you ever been featured in a documentary like CURIOUS?
DAVIS: No.
Q. Do you think the kind of visibility PBS will bring to you and your work could help with the FDA approval process, and with funding this and other research?
DAVIS: I don’t know about the approval process. My guess would be that it can’t hurt but I am skeptical that it will really help. I definitely hope that it helps in some way though. At this point, it could help get patients to fill our trials faster and that could ultimately help the approval process move quicker. However, I am sure many positives that I have not thought about will come out of the PBS show.
Q. What other research are you working on now?
DAVIS: In addition to our work on therapeutics, we are working on creating new materials for moving ions. Why is this important? We are attempting to synthesize materials to make safer and longer-lasting batteries.
October 4th, 2007 at 9:29 pm
Excellent show. I would like to get my mom, a stage-4 lung cancer patient, into a clinical trial and I am encouraged by Dr. Davis’ research. Thanks for bringing it to my attention.
October 5th, 2007 at 3:16 pm
Extremely inspirational program. I commend Mark for his action. I only wish that all of these hospitals and businesses would coordinate resources to find a cure. With so many great minds working on finding a cure and so much money being spread out - we’d have a cure if more worked together.
October 11th, 2007 at 9:45 pm
I liked the show. I missed the part where a crude explanation was given how the delivery system worked (was making dinner) Is it possible to see a copy of te show on the internet?
My sister in law is has 13 3 to 6 mm HCC metastasis in her lungs. The HCC tumor in the liver was succesfully removed in Mainz 3 months ago. Would this drug and delivery system also be effective for HCC metastasis in the lung?
October 14th, 2007 at 11:49 am
This absolutely fantastic story ought to be viewable online asap. It was truly inspirational. Move over NOVA (as excellent as NOVA has been, science often seems to take second place these days: e.g., how to make a Samaurai sword, anyone? Curious is filling a void in 13’s science coverage this Fall).
Congratulations to the producers and to the participants!
October 16th, 2007 at 10:18 pm
I stumbled onto this great program. People like Mark Davis inspire me to be a better human being and always look for better ways to help humanity. Only wish I knew about this 5 years ago when my Mom was diagnosed with Breast Cancer, like Mary…she now has severe hearing loss from the chemo!
Again, THANK YOU PBS for continuing to inform and inspire us!
October 17th, 2007 at 12:00 am
What a great program.
I was recently had surgery to remove a tumor from my right ovary and I am now receiving Chemotherapy treatments.
I was so inspired by the whole program that I will tell my friends and family about this new technology and the wonderful work that is being done by all involved. I hope that this will help many more cancer patients like Ray to give them hope and a better quality of life.
October 17th, 2007 at 1:30 pm
Impressive program, 18 hours after watching the program, I’m still fascinated by how humanity struggles against nature. Thank you.
October 17th, 2007 at 9:07 pm
Everyone: SHOUT about this discovery from your rooftops! Give anyone ever touched by Cancer reason for hope. Thank God for you, Mary & Mark Davis.
October 17th, 2007 at 9:24 pm
Outstanding work! This is a program every middle school should show to their students to inspire a passion for the great adventure that is science. Please make it available online.
October 18th, 2007 at 1:55 am
I just finished watching the program and was impressed with what I saw. To see Ray’s life be changed and how IT-101 came to be was amazing. Keep up the fantastic work!
October 18th, 2007 at 5:38 pm
the segment on Mark Davis’s drug was riveting. Please tell me if this will be available online or on DVD. Would love to use it for educational purposes.
October 20th, 2007 at 9:50 pm
Please make this episode available on DVD!!! Those of us who saw it need to be able to show it to others. It’s very inspiring.
November 4th, 2007 at 5:47 am
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November 13th, 2007 at 12:45 am
I have ovarian cancer and have been receiving Chemo since 2003. What I particularly liked about your discovery is that it attacks only cancer cells, not normal cells. I have told my oncologist about IT-101 and am going to printout everything I can find and give it to him. Your wife’s suffering has brought about something wonderful…IT-1-1…. Thank you for all your hard work…..
November 17th, 2007 at 1:41 am
I was excited to stumble on this series. It’s really great. I’m recommending it to my nephew who is 10 years old but capable of at least 8th grade math. He wants to do biomedical research when he grows up. I hope he can see this program ASAP. It’s much further advance (and interesting) than his 5th grade science and math class. Yipee!
December 8th, 2007 at 4:34 pm
Yes, DVD’s would be great! The world needs to see this remarkable man and treatment. I tell everyone I know about the trials. 3-7 years is too long! Another remarkable product that is helping soooo many people is Mona Vie. It’s about nutrition. It feeds your cell what they need to function properly. It’s a super antioxidant and much more. A free radical destroyer. We’ve made a DVD about it and it has made a huge difference in helping people understand what it is. IT-101 needs the same type explanation. Hopefully the program will air more often!
January 3rd, 2008 at 2:27 pm
Dr. Davis
Keep exploreing new options!
Sorry that it’s too late for my husband’s lung cancer.
January 3rd, 2008 at 11:14 pm
My daughter (39 years old, with three children) has stage 4 metastic breast cancer, that has spread to her lungs, brain, liver and bones. Can she be considered for a trial with IT-101?
January 3rd, 2008 at 11:33 pm
Dr. Davis, I was extremely impressed with the results of your clinical trial. Your hard work and dedication brings hope to many people who have been touched by this devastating decease. I lost my 9 yrs old son to cancer and I hope that your work provide a much needed cancer treatment option for the benefit of mankind. Thank you!
January 4th, 2008 at 3:55 am
Thank you so much for the inspiration and hope your discovery brings. I am interested in knowing, if and how, my sister who has advanced pancreatic cancer with liver involvement, could be considered for using IT 101? Her chemo regimens have been working but she is presently struggling with low white blood cell counts making continued treatments difficult. I am anxious to hear your response.
January 4th, 2008 at 11:34 am
This is what Bud saw on TV last night.
Dottie
January 9th, 2008 at 11:10 am
Dr. Davis and the people who produce curious. I want to commend you on such a clever way to attack this atrocious disease. I have not had to deal with cancer on a familial level, though I did do somethings to assist them through the horrible experience of chemotherapy. I am going to start sending the word out to more people about this protocol and hopefully can expand the quality of peoples lives as well as their longevity. I applaud you and all your staff for their hard work. I also want to thank curious for introducing it to me, what a wonderful show that I will keep watching. Thank you all so much for educating the public.
January 10th, 2008 at 1:40 am
Please,I can’t remember the date of a very special program that was aired,but it was about RNA1.Can you please let me know.My grandaughter has the same problem as the lady that couldn’t see,and my daughter doesn’t believe what I told her about what I saw in regards to this.Is there a video or dvd that I can purchase?Thanks–God bless you all
January 11th, 2008 at 12:17 am
i have actinic keratoses on my hand, and maybe my arms also. but one biopsy was positive.my treatment is with efudex, but is there a better way? and how serious is this type of cancer?
January 11th, 2008 at 10:06 am
Dr. Davis,
I think the work you have done and are doing is fantastic! I wish you and your family all the best and I look forward to following your progress in the months and years to come!
Thanks!
January 11th, 2008 at 10:40 pm
This is such an exciting trial. I have recurrent breast cancer. Hoping it is a cure for stage IV breast cancer someday.
January 12th, 2008 at 4:09 pm
Just saw this last night via WGBH Boston…. a bit surprise that WGBH Boston did not air this earlier.
Up there with NOVA… BUT much more down to earth. I could understand the basic concepts behind the science because of the way it was presented. Concepts are simple and elegant ! Exhibiting the deep knowledge and creativity behind the idea.
The show grabbed me… it was aired around midnight and I was ready to go to bed, but instead I watched the whole show.
Keep up the good work, CURIOUS. Will definitely on the watch out for more shows here up north.
Too bad, my twins boys chose to stay out east for college. What a great asset Cal. Tech. has for their students !
January 13th, 2008 at 6:40 am
Dr. Davis, I wish you much success. I lost my first wife to ovarian cancer after 33 years of marriage . I lost my second wife to breast cancer after 5 years .The chemo treatments had such terrible side effects. I took care of both wives Janie suffered off and on for 7 years, Denise
tried to beat cancer for over 2 years. Treatments on Janie included taxol which take you close to death and back. God bless you I hope your drug gets approved.
January 13th, 2008 at 11:08 pm
I found this program very exciting. I have friend with rare form of cancer, GIST. I’m hoping this will new research will help. I’m an ovarian cancer survivor myself, so hearing about Dr. Davis research is very exciting.
January 14th, 2008 at 8:39 pm
Dr.Davis,God Bless you.As I watched the t.v. Saturday night I
thought I was dreaming when I saw your program.I have just lost my mother due to 4 cancers.She fought for 11 months. In May 07 the cancer was stable.But,it won.My mother lost her battle 10/14/07.I had never known anyone with cancer.As a caregiver it was hard.I’m pleased
that your wife is doing well and that she pushed you to find a cure
for this awful disease.To many people are dying from this.I hope Ray continues to do well.I will continue to follow your research.
thank you so much
January 15th, 2008 at 2:51 pm
Thank you for this GREAT PROGRAM!!!
Mark Davis is a ROLE MODEL for teens, they must know about him!
January 16th, 2008 at 12:09 am
Dr. Davis, I just saw the rebroadcast documenting your work. What you and your team(s) have accomplished to this point is amazing. I like so many others have been touched by cancer, for me it’s been through family members who have had to fight. I just want to encourage you and others who have given their lives to this research to keep going. Our prayers are with you.
January 19th, 2008 at 12:48 am
Excellent new program. Dr. Davis proves once again that sometimes the best way to achieve success in a particular field is to turn to an entirely different discipline,
This is why it’s vital in this country that we start ‘cross-pollinating” various scientific fields of study; just to see what happens.
January 19th, 2008 at 9:56 am
Do you believe the fuel cell information in this link? Thanks, Bryan
http://logicalscience.blogspot.com/2006/11/hydrogen-economy-no-backing-in-physics.html
January 20th, 2008 at 1:59 am
I am inspired! Dr. Davis. Let me come to work for you. I can educate the world! I was nearly in tears. I believe you have found a cure for cancer… the polymer is brilliant! Funny that “Troy” was running on AMC and “Curious” came on! Meant to be!
January 20th, 2008 at 6:14 pm
Hi Mark,
with your big respect i am just asking you if you could help me please, where to get some of your drug to cure for cancer my Mom Doni, have a “Bladder Cancer”, I am truly appreciate.
Hoping Your Kind and consideration.
Respectfully Yours,
Mhel
January 23rd, 2008 at 5:45 pm
Your research is brilliant! I have been on line reading everything I can about your IT-101 and the City of Hope trials. I’m hoping that you are able to get some trials set up here on the east coast. Boston is only two hours from where we live in Maine, and I would be able to bring my sister there for treatment. She has the spirit of a survivor, but she needs a treatment like this to turn her breast cancer around.
January 27th, 2008 at 7:58 am
Did anyone catch the name of the tree the bark came from in China? Please post. I am also trying to find a recording of the entire episode. It was called “Survivor” Thanks, plaese post or e-mail datasouthtech@yahoo.com
January 29th, 2008 at 3:38 am
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January 29th, 2008 at 10:29 pm
There is no happiness like that of being loved by your these returning vnhxtrrpczayd was very pleasant or desirable no magnet drew me.
January 31st, 2008 at 4:53 pm
Dr. Davis, My brother has stage four Lung Cancer. He lives in N.H.
I told him about the PBS program and your wonderful work. I am trying to find out how he can get more information and possibly get into the trial. The cancer has spread to his bone and lymph nodes. Please help. He’s 56 years old. Thank you!
January 31st, 2008 at 11:29 pm
Is there a clinical trial in Florida?
February 1st, 2008 at 11:27 pm
I have heard great things about these trials and am very interested in learning where I can purchase a DVD of the brodcast or learn more about how I can watch it. I have a family member in desperate need of hope and would like to know if this could be an option!
Can anyone point me in the right direction?
February 2nd, 2008 at 12:55 pm
Thanks for sharing
February 7th, 2008 at 2:47 am
Yes. there are messages here from the east coast. Are there any trials for it101 there. my father also lives in new hampshire with lung cancer and is only 2 hours away from boston. hope can be in any city. it;s in everybodies heart.
February 9th, 2008 at 1:56 pm
The tree is Camptotheca acuminata, and called “Xi Shu” (literally happy tree) in Chinese. The anti-cancer agent is Camptothecin, which is a key element of IT-101.
February 9th, 2008 at 9:05 pm
I’d prefer reading in my native language, because my knowledge of your languange is no so well. But it was interesting! Look for some my links:
February 10th, 2008 at 2:32 am
Have Father with Prostrate camcer coud this be a posibel treatment?
February 10th, 2008 at 3:43 am
Dr. Davis,
My uncle Bob Ritchmeier, has stage four lung cancer, through out his battle he has been a pillar of strength to all of us, smiling even when news from the doctor is not favorable. Last report from the doctor is that the cancer is advancing and that he has till the end of summer.
Where can one find information as to if this is an option for Uncle Bob.
February 10th, 2008 at 1:01 pm
Q. Where does the IT-101 trial stand now?
DAVIS: It is finishing the Phase I trial and will be moving into several Phase II trials (Phase I can be for all types of cancer but Phase II has to be in specific cancer types).
Have you chosen the types of cancer you’ll use for Phase II?
I have a friend with Mesothelioma. He is having an operation and probably chemo after. Would he qualify for your trials?
February 10th, 2008 at 4:52 pm
What a great breakthrough and fascinating program on and off the air! I have passed the information along to friends who have cancer. This treatment needs to be approved as quickly as possible to save lives!
February 23rd, 2008 at 3:08 am
purchasing a new carriage. she said the idea of his marrying Miss flash myspace layouts ‘flash with the heavy flesh that now cumbers my soul. Of the fanatic s
March 3rd, 2008 at 12:27 pm
My sister-in-law has ‘head and neck’ cancer ,its in second stage and she is in India.I want to know will IT-101 work on this kind of cancer and is it available in India and how much will be the expence on it?
thanks I am looking forward to you
Suman
March 12th, 2008 at 3:19 pm
Hello Mr. Davis,
I was interested in the IT 101 clinical trial, but was told that this
study is closed. A family friend of ours referred us through Dr.
Mercedes Brenneisen. My father is 60 years old and was just diagnosed in
February with adenocarcinoma in his right lung. His doctors state that it is
stage 3B, however he has had no CT scans to see if the cancer has
spread to anywhere else in the body. We have been through a great ordeal,
my father is uninsured as he recently lost his business in October. We
are desperate to get some kind of treatment started. Can you please
inform me of the process of getting him seen by a City of Hope doctor
and/or getting involved in a clinical trial.
Thanks for your time,
Brianne Walker
March 12th, 2008 at 3:19 pm
Hello Mr. Davis,
I was interested in the IT 101 clinical trial, but was told that this
study is closed. A family friend of ours referred us through Dr.
Mercedes Brenison. My father is 60 years old and was just diagnosed in
February with adenocarcinoma in his right lung. His doctors state that it is
stage 3B, however he has had no CT scans to see if the cancer has
spread to anywhere else in the body. We have been through a great ordeal,
my father is uninsured as he recently lost his business in October. We
are desperate to get some kind of treatment started. Can you please
inform me of the process of getting him seen by a City of Hope doctor
and/or getting involved in a clinical trial.
Thanks for your time,
Brianne Walker
March 21st, 2008 at 1:10 am
Great story of Mark Davis and Mary. saw it on PBS here in Dallas,TX and you’ve got a new fan…. me and my wife really enjoy your site. we’ll be visiting frequently.
March 23rd, 2008 at 1:26 am
consumption, and puts every body more or less, but particularly b37MXfm6×3 and to assist them in those losses and misfortunes which might
March 24th, 2008 at 7:41 am
I’d prefer reading in my native language, because my knowledge of your languange is no so well.
April 7th, 2008 at 6:54 pm
Dr Davis, My daughter has lung cancer-a squallus lesion. She has had chemo, radiation and a targeted drug Tarseva. Could she be a candidate for your it101 therapy. She is 45 yers old. If not what else could you recommend. Thank you,Anne
April 8th, 2008 at 10:45 pm
37 yrs. old family member was diagnosed with pancreatic cancer on Dec. 2006 and given one to two year survival. He has recieved chemo. to date the cancer has not spread and as a matter of fact the lesion at the mid pancreas reduced to one cm. Unfortunately his doctors at Sloan Ketterin, NY still feel he is inoperable secondary to the proximity of major vessels. His case is very sad not only for him but his wife and 2 small children.. In addition like your program of the gentleman with pancreatic ca. the systemic chemo therapy has wiped him out. We were very encouraged from IT-101 and wondering if he could be a candidate for it to shrinking the tumor further to make him a surgical candidate. I would appreciate a reply. Thank you
June 26th, 2008 at 9:16 pm
Is the DVD of the program shown on TV available for purchase?
July 17th, 2008 at 9:27 pm
See on Google Dr.Simoncini’s web site on cause and cancer cure.He is an oncologist with some 30 years of using a very safe substance at 5% that cures cancer which Dr.Simoncini believes is caused by fungi!Read his new book in Englishit is amazing.He is no self taught quack,but a trained medical doctor/surgeon/oncologist working in a clinic in Rome.
August 11th, 2008 at 8:24 am
My husband has stage 4 colon cancer metatstic to liver, lungs, and bone. He was diagnosed in March 2006. Is your research in Phase 2 yet and would he be eligible for the study. Your attention to this matter would be deeply appreciated.
Harriet Dalrymple
Charlotte, NC
October 11th, 2008 at 4:32 pm
Dr.Davis, my nephew, 5 years old, has been diagnosed with Osteo sarcoma. It is the 3rd or 4 th stage. Is there a way the family can get in touch with you. Can he be a cndidate for IT 101
November 12th, 2008 at 8:28 pm
Dr Davis,
Thank you for giving my dad (RAY NATHA) the opportunity to enjoy a few extra years.
Dad passed away on 25 October 2008.
November 23rd, 2008 at 11:18 pm
Dear Dr. Davis,
My daddy has been diagnosed with Lung Cancer. He is 76 years old. He is not interested in taking chemo or radiation. Currently, he not experiencing any pain or weakness. He has lost a great deal of weight in the last couple of years. He gets tired when he walks but still works in his garden. He does not complain at all. He has a mass in his left lung and nothing in his right lung. However, the doctor feels that he would not survive with just his right lung. Could he be a canidate for IT-101 ? Dr. Nick Crisson is his oncologist at the Cancer Center in W-S, NC. We would appreciate any response and help that you could provide.
December 19th, 2008 at 9:28 am
My brother, 36 years old was diagnosed with Osteosarcoma 2 years ago. He had his leg amputated 1 year ago, he now has lung mets in both lungs which surgery cannot help. The only option he is given is Chemo. I don’t think he can withstand any more chemo. Please let me know if he would be elligible for the IT-101. Any help would be appreciated.
January 25th, 2009 at 11:59 am
My husband has prostate cancer with his PSA at 9.5 and gleason at 6. Could he be a candidate for IT 101?
January 25th, 2009 at 11:53 pm
Dr. Davis,
My mother has stage-4 breast cancer with mets to her liver and bone. Her liver is now over 50% compromised and the doctors won’t give her chemo because she is too weak to handle the side effects. She is approaching end-stage but they are telling us fluctuating predictions of time left. She is currently on palliative care. I saw the documentary this morning and its pretty much my last hope. Is there any way that my mother can get on it-101 immediately? I want to do whatever I can, I’m only 23 and am not ready to lose my mom!
February 6th, 2009 at 11:39 am
PLEASE MY BROTHER IS A DR. AND HAS BRAIN TUMORS AND INTESTIONAL CANCER I NEED TO GET THE MEDICATION TO HIS ONCOLOGIST SO HE CAN START TREATMENT THEY GAVE HIM 6 MONTHS TO LIVE 4 MONTHS AGO PLEASE HELP ME SO I CAN HELP HIM. MY PHONE 914 582 4508 IF I DO NOT ANSWER PLEASE LEAVE A MESSAGE I WILL GET BACK RIGHT AWAY LINDA FIORELLO MY BROTHER NAME IS DR. WILLIAM KNORR FROM NEW YORK
February 6th, 2009 at 7:29 pm
Dear Dr. Davis,
My name is Ellie. I have been treated for ovarian cancer twice before. Each time was just about 10 years apart. I was treated with chemo therapy each time. I was just diagnosed with colon cancer. I am in my seventies, and am wondering if you have treated anyone for colon cancer. I would be interested in any information regarding this. I also am very interested in participating in one of your studies, if that would be a possibility. I greatly would appreciate your response.
February 18th, 2009 at 8:34 pm
I have stage 4 breast cancer estrogen positive. I’m on my second time with cancer since 8 years. It returned in my oviars, and lung, and adrenal glands, omiues area, and bone and liver.
I live in Virginia and heard of phase 2 in newport news. Where can I go to find it being used for breast cancer. I pray every day that the IT-101 for breast cancer trails. Do you know when?
March 1st, 2009 at 9:12 am
Dear Dr.Mark:
I am Chinese.My daddy has been diagnosed with Lung Cancer. He is 65 years old. He is in taking chemo about 5 months. Now, he is very weak. He has a mass in his left lung and nothing in his right lung. Now, the doctor thinks the cancer has been transfered to bone and head. My mom and I feel very sad. I know you from the TV(CCTV). From you, I see hope. Could he be a canidate for IT-101 ? Can you tell me your telphone number and Email, I will call you. We would appreciate any response and help that you could provide. Thank you very much!!!
March 1st, 2009 at 9:17 am
Dear Dr.Mark:
I missed an important thing. Doctor diagnosed my father’s cancer is T4N2M1. Could the IT -101 help him?
March 25th, 2009 at 12:03 am
Thank u so much for ur research….as an x breast cancer patient…I am grateful to hear about ur discovery and impending help for others
April 27th, 2009 at 11:32 am
Dr.Mark
I am Chinese, It’s depressed for everyone that my Aunt is in cancer again. She is a great woman, self-confident and strong-minded. She was just recover from mammary cancer one year ago. Because of her optimism, she became a dancer during the cure, and a teacher for many villagers. Now She has been diagnosed with Lung Cancer. It seems like chemo is just lengthen life for years or months. My brother her son is just 21 years old, just begin his college. Uncle is an engineer in a factory and seems not good at managing family. The family can’t loss her and neither for us. I konw something about IT101. It’s in Phase II trials and may take years. It also seems hopeless to go abroad and be a patient of the trial for a common family in China. I have no idea. Just ask for your opion with some possibility. Best Wishs!
October 14th, 2009 at 7:28 am
When can we see IT-101 on the market ?
In Sfax, Tunisia (North africa), we have a great number of patient by cancer. We usually hear by death with cancer. We are afraid and waiting for IT-101 ! Thanks Mark and Mary DAVIS.
Sawssen HARIZ
October 25th, 2009 at 3:17 am
Hi Dr.,
You were a sprinter. You are Marathon Man now, but you are still sprinting. You will be recognized as The Greatest Runner of all time, in all categories of running, very soon. As you have given your life to save others, you will be given back yours multiplied by the joy you are bringing to the countless victims of this most terrible and dreaded plague.